Mechanism of Streptomycin Resistance inLeptospira biflexaStrain Urawa
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چکیده
منابع مشابه
Streptomycin resistance in a streptomycin-producing microorganism.
Cell-free extracts of Streptomyces bikiniensis contain an adenosine 5'-triphosphate-dependent kinase which inactivates streptomycin (Sm) and dihydrostreptomycin by phosphorylation. The products have been identified as streptomycin 6-phosphate and dihydrostreptomycin 6-phosphate. Activity was not present in logarithmic-phase cells, which were susceptible to 25 mug of Sm per ml. In stationary-pha...
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Resistance (R) factor-mediated streptomycin (Sm) resistance differs from classical, high-level, chromosome-borne Sm resistance in its dominance over sensitivity and in the level of its effectiveness (in Escherichia coli approximately 25 mug/ml versus >2,000 mug/ml). In addition, an R factor-containing strain, unlike high-level Sm-resistant bacteria, showed an inoculum effect with respect to its...
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WALTHO, JUDITH A. (University of Melbourne, Victoria, Australia), AND B. W. HOLLOWAY. Suppression of fluorophenylalanine resistance by mutation to streptomycin resistance in Pseudomonas aeruginosa. J. Bacteriol. 92:35-42. 1966.Fluorophenylalanine-resistant mutants (fpa-r) of Pseudomonas aeruginosa have been isolated. By cotransduction analysis, the mutations were shown to have at least two chro...
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NIQUE opportunities for the study of mutations, both spontaneous and U induced, have been offered by what we may call the " phage-resistance system '? of bacterial changes from sensitivity to resistance to bacteriophages. In studying this system it is easy to work with large numbers of bacteria (1 x 108 per Petri dish) ; and if sufficient quantities of phage are added, all sensitive bacteria wi...
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Bryan, Betty E. (University of Rochester, Rochester, N. Y.). Genetic modifiers of streptomycin resistance in pneumococcus. J. Bacteriol. 82:461-470. 1961.-Streptomycin-resistant mutants arising spontaneously in pneumococcus vary widely with respect to the maximal concentrations of streptomycin which they resist. A small random sample of these mutations tested for linkage are allelic or closely ...
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ژورنال
عنوان ژورنال: Microbiology and Immunology
سال: 1988
ISSN: 0385-5600
DOI: 10.1111/j.1348-0421.1988.tb01425.x